Stress can diminish our ability to assess new threats, according to new research.
The new finding runs counter to the conventional view that stress enhances our ability to detect and adjust to these changing sources of threat.
“Stress does not always increase perceptions of danger in the environment, as is often assumed,” explains Candace Raio, a postdoctoral researcher at New York University and the study’s lead author.
“In fact, our study shows that when we are under stress, we pay less attention to changes in the environment, potentially putting us at increased risk for ignoring new sources of threat. As a result, stress can reduce the flexibility of our responses to threats by impairing how well we track and update predictions of potentially dangerous circumstances.”
Although learning to predict threats in our environment is critical to survival, the study’s authors note, it is equally important to be flexible in order to control these responses when new sources of threat change—for instance, from an oncoming car to an out-of-control skateboarder.
To test our ability to learn to flexibly update threat responses under stressful conditions the researchers conducted a series of experiments that centered on “Pavlovian threat-conditioning.” Here, the subjects viewed images on a computer screen. The researchers coupled the appearance of some images with a mild, electric wrist-shock, serving as a “threat cue,” and never paired other images with a shock (“safe cue”).
A day later, half of the participants underwent a laboratory procedure designed to induce stress—this “stress group” placed their arm in an ice-water bath for a few minutes, which elevated two known stress hormones (alpha-amylase and cortisol). Later, all of the study’s subjects repeated the threat-conditioning procedure. This time, however, the cue outcomes switched: the earlier threatening cue no longer predicted shock, but the formerly safe cue did.
While the subjects viewed the images, the scientists collected physiological arousal responses in order to measure how individuals anticipated the outcome of each cue.
On the second day of the experiment, the stress group was less likely to change their responses to threats (the formerly safe visuals that were now paired with shocks) than was the control group, an indication that stress impaired its ability to be flexible in detecting new threats. Specifically, stressed participants showed reduced physiological response to the new threat cue, suggesting that they did not fully switch their association with this cue from safe to threatening.
The researchers then applied a computational learning model to further understand how stress affects flexibility in decision making. This analysis revealed a learning deficit for the subjects under the stress condition—specifically, stress affected an attentional signal (“associability”)—that participants used to update the cue associations. In short, participants’ stress lead to a slower rate of learning.
The research appears in the journal Proceedings of the National Academy of Sciences.
A grant from the National Institute of Mental Health supported the research.
Source: New York University