painkillers
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Compound may treat neuropathic pain without opioids
Researchers have taken a key step forward to a new, non-opioid approach to treating neuropathic pain.
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Access to prescription opioids may reduce overdose deaths
"Our findings suggest that restoring easier access to opioid pain medications may protect against fatal overdoses."
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Finding may explain variation in similar painkillers
A new study may clarify why NSAIDs like ibuprofen and aspirin can have unexpected and unexplained effects on diseases like heart disease and cancer.
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Living ‘nerve circuit’ could test opioid alternatives
Half a million people in the US have died from opioid overdose in the past 10 years. Researchers hope a living bioengineered nerve circuit can change that.
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Team maps how brain signals trigger pain
A new discovery of how a potent neuropeptide binds to a brain receptor involved in causing human pain could lead to new painkilling medications.
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Ibuprofen changes liver metabolism in mice
"Many commonly used drugs such as ibuprofen are being overused and should not be used for certain conditions such as mild pain."
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Most people who need anti-overdose drug don’t get it
Naloxone can save the lives of people who take high-dose opioids, but less than 2% of those who need it actually get it.
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Disposal packets make it easier to get rid of leftover painkillers
Many parents keep their own and their children's unused opioids, but a simple take-home pill disposal packet can help reduce risk.
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New opioid has speedier pain recovery than morphine
Morphine can mask pain, but also increase patients' sensitivity to it. A new opioid, ZH853, cuts out that side effect and sped up recovery in rats.
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To fight the opioid epidemic, take drug makers to court?
While suing drug makers that produce opioids hasn't been very successful in the past, researchers say the strategy could work better now.
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Aspirin-like drug may block protein needed for hearing
A drug prescribed for arthritis and pain may inhibit a protein key to hearing—just as doctors are considering using the drug for other diseases.
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Can this new painkiller evade the flaws of opioids?
A synthetic compound called UKH-1114 works as well as a widely used drug for relieving pain in mice—but at much lower doses and for longer.