More people opt in for colorectal cancer screening by mail

Sending tests in the mail can boost rates of colorectal cancer screening, research shows.

In collaboration with the Mecklenburg County Health Department in Charlotte, researchers with UNC Lineberger’s Carolina Cancer Screening Initiative examined the impact of targeted outreach to more than 2,100 people insured by Medicaid who were not up-to-date with colorectal cancer screening.

The project resulted in a nearly 9 percentage point percent increase in screening rates for patients who received a screening kit in the mail compared with patients who just received a reminder, and it demonstrated that their method could serve as a model to improve screening on a larger scale. The findings appear in the journal Cancer.

50,600 deaths each year

The American Cancer Society estimates that more than 97,000 people will receive a colorectal cancer diagnosis in the United States this year, and the disease will result in approximately 50,600 deaths. It is third most common type of cancer in the United States, and the second leading cause of cancer death.

“Preventive care amongst vulnerable populations rarely rises to the top of the mental queue of things that need to get done.”

While colorectal cancer screening has proven effective in reducing cancer deaths, researchers report too few people are getting screened. Current guidelines from ACS recommend regular screening with either a high-sensitivity stool-based test or a structural (visual) exam for average-risk people aged 45 years and older, and that colonoscopy should follow all positive results.

Despite these recommendations, studies have identified notable gaps in screening rates, including by race, geographic region, and other socioeconomic factors. Among patients who are insured, people with Medicaid have the lowest rates of colorectal cancer testing.

“There has been a national push to increase colorectal cancer screening rates since colorectal cancer is a preventable disease, but screening rates are only about 63 percent, and low-income, and otherwise vulnerable populations, tend to be screened at even lower rates,” says first author Alison Brenner, research assistant professor in the UNC School of Medicine’s internal medicine department.

Test kits in the mail

For the project, researchers either mailed reminders about colorectal cancer screening and instructions on how to arrange one with the health department, or reminders plus a fecal immunochemical test, or FIT kit, which can detect blood in the stool—a symptom of colon cancer. The patient completes the test at home and returns it to a provider for analysis. Patients who have a positive FIT kit result will be scheduled for a colonoscopy.

The researchers worked with the Mecklenburg County Health Department staff, who coordinated the reminders and mailings and ran the test analyses. They also partnered with Medicaid care coordinators to provide patient navigation support to patients who had abnormal test results and required a colonoscopy.

Twenty-one percent of patients who received FIT kits in the mail completed the screening test, compared with 12 percent of patients who just received a reminder. Eighteen people who completed FIT tests had abnormal results, and 15 of those people were eligible for a colonoscopy. Of the 10 who completed the colonoscopy, one patient had an abnormal result.

“Preventive care amongst vulnerable populations rarely rises to the top of the mental queue of things that need to get done,” Brenner says. “In North Carolina, many Medicaid recipients are on disability. Making something like colorectal cancer screening as simple and seamless as possible is really important. If it’s right in front of someone, it’s more likely to get done, even if there are simple barriers in place.”

Next steps

Brenner says the study shows the potential to harness resources like the county health department for health prevention services.

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The researchers plan to move forward to study whether they can implement their approach on a larger scale, and to understand all of the cost implications, says Stephanie Wheeler, associate professor in the UNC Gillings School of Global Public Health and the study’s senior author.

“This is looking at expanding the medical neighborhood—to harness community resources to target patients and in this case, insured patients, who are maybe not getting this from a primary health care organization, and how to increase screening rates in these types of vulnerable populations,” Brenner says.

UNC Lineberger supported the study through a Tier 2 Stimulus Award, the Centers for Disease Control and Prevention, and the National Cancer Institute Cancer Prevention and Control Research Network. Individual researchers had support from the National Institutes of Health and the University of North Carolina Royster Society of Fellows.

Source: UNC-Chapel Hill