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How to stop deadly bat virus from going global

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If the deadly Nipah virus, transmitted to people by bats, adapts to more efficient human-to-human transmission, "then in our globally connected world, humanity could face its most devastating pandemic," says Stephen Luby. (Credit: Ryan Poplin/Flickr)

A virus spread by bats is killing people in Southeast Asia and could pose the threat of a global pandemic.

It usually starts with a fever and headache, maybe some coughing and a disoriented feeling. Before long, inflammation of the veins, arteries, and brain sets in, a seizure takes hold, and you lose consciousness. Seven out of ten cases end in death. Of those who survive, one-third have permanent, crippling neurological disorders.

That’s the fate of people infected with the Nipah virus in Bangladesh, where outbreaks occur in most years.


People outside Southeast Asia have reason to be concerned too, says Stephen Luby, professor of medicine at Stanford University.

If the virus adapts to more efficient human-to-human transmission, “then in our globally connected world, humanity could face its most devastating pandemic,” Luby writes in a commentary published in the journal Antiviral Research.

Discovered in 1999, the virus can be traced to Pteropus bats, which carry the virus but are immune to it.

In Bangladesh, these bats transmit the virus to humans through raw date palm sap, which the bats are known to lick and urinate in as it is harvested for human consumption. Children love the treat with puffed rice in the morning.

Sustained person-to-person transmission of Nipah through contact with bodily secretions has been limited so far. Still, there is significant cause for concern that Nipah could spread faster and wider.

Pteropus bats roam over a range stretching from Pakistan across South and Southeast Asia, up the coast of Southern China and down into Australia. Climate change and other environmental factors could expand the bats’ range.

Many strains of the virus are capable of limited person-to-person transmission. It’s a ribonucleic acid (RNA) virus, which has the highest known rate of mutation among biological agents. If a more efficient human-adapted strain developed, it could spread rapidly in highly populous South Asia before spilling into other regions.

Steps to take

The global community must do a better job of estimating and managing the risk, Luby says. That will require stepped-up study of how the virus is transmitted, closer observation of infected people, and consideration of vaccinations for at-risk communities.

Rich countries need to help improve poor countries’ health care systems—specifically, making sure health care workers have access to protection such as gloves and hand-washing—to help prevent spread.

In densely populated Bangladesh, health care providers who treat Nipah patients typically lack gloves and masks, while patient attendants often lack soap and water for hand-washing.

Beyond stopping the spread of Nipah, such measures would also reduce the risk of influenza and other disease pandemics.

“I think it important that taxpayers in the US recognize that investments in prevention in low-income, high-risk countries can protect their own lives.”

Source: Stanford University

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