U. ROCHESTER (US) — Exposure to school-age children raises the odds that a person with lung disease who catches a cold will actually suffer symptoms like a runny nose, sore throat, and cough, a new study shows.
For the study, published in the Journal of Clinical Virology, researchers drew upon a databank of 1,000 samples of sputum and nasal secretions from people with chronic obstructive pulmonary disease or COPD. The results come as a surprise, says Ann Falsey, professor of medicine at the University of Rochester and an infectious disease expert at Rochester General Hospital.
“Before we conducted this study, I would have expected other factors, perhaps the severity of underlying disease—the state of the patient’s general health—to indicate who would actually suffer symptoms from their colds,” says Falsey.
“Instead, contact with school-age children is the only risk factor we found, and it increases both the risk of infection and also the risk of suffering symptoms once you’ve caught a cold.”
Many studies, including this one, have found that being around school-age children increases the risk of infection, but the new findings go one step further. Of people who come down with colds, the course of the infection is much more likely to be worse in people exposed to children.
In everyday life, many people have no symptoms and don’t even realize it when they catch a cold. It comes as no surprise that Falsey and first author Anurag Gandhi found that more than one-third of people infected with a rhinovirus, the bug that causes most colds, had no symptoms.
But further analysis of the data showed that of those people who were infected, people whose infection turned into real-life symptoms—congestion, runny nose, sore throat, hoarseness, and so on—were about twice as likely to have contact with school-age children as people whose infections did not become symptomatic.
While the study wasn’t designed to tease out a possible explanation, Falsey says the results may be due to the fact colds run a bit more rampant in young children because they haven’t had many years to build up immunity—and children’s colds tend to be worse overall.
“We know that kids shed more virus longer when they get a cold,” Falsey says. “It may be that your chance of developing cold symptoms is related to the amount of virus you’re exposed to, and if you’re around small children, you’re exposed to more virus. The idea makes sense, but it’s speculation at this point.”
To avoid colds, practice good hand hygiene. Wash hands often, especially after sneezing or covering your mouth when coughing. Avoid touching the eyes and nose as much as possible—and try to avoid sick children.
“We all know that children are efficient germ-spreading vectors,” Falsey says, “and we know that young children oftentimes don’t have ideal hygiene habits. It’s not unusual for them to accidentally sneeze in your face, for instance. If you have a grandchild who is sick, it may simply be smart to plan a visit for another day.”
The study relied upon close monitoring and sampling of 127 people with emphysema who were evaluated six times each during one year. At all visits, nasal secretions were sampled, and sputum samples were obtained when available.
Gandhi and Falsey’s analysis of the resulting 1,000 samples of bodily fluids, stored for nearly a decade at minus 112 degrees Fahrenheit, also turned up another unexpected finding: Adults who were on home oxygen use were somewhat protected against the added risk posed by schoolchildren.
Again, the study was not designed to answer why, since the finding was unexpected. It could be, for instance, that young children were more apt to avoid close contact with adults who were wired up with tubes and apparatus that are scary to many children.
Source: University of Rochester