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Rethink dosage of calcium, vitamin D

PENN STATE (US) — The majority of Americans up to age 70 are getting enough vitamin D and calcium, according to a new Institute of Medicine report.

The daily recommended intake (DRI) values are based on findings from nearly 1,000 published studies as well as testimony from scientists and stakeholders, which confirm the roles of calcium and vitamin D in promoting skeletal growth and maintenance and the amounts needed to avoid poor bone health.

The dosage range for vitamin D is based on a review of hundreds of studies and reports on other possible health effects, such as protection against cancer, heart disease, autoimmune diseases, and diabetes.

While these studies point to possibilities that warrant further investigation, they have yielded conflicting and mixed results and do not offer the evidence needed to confirm that vitamin D has these effects.

“There is abundant science to confidently state how much vitamin D and calcium people need,” says Catharine Ross, professor of nutritional sciences at Penn State, who chaired the committee that issued the report.

“We scrutinized the evidence, looking for indications of beneficial effects at all levels of intake. Amounts higher than those specified in this report are not necessary to maintain bone health.”

Daily Dosage

Most Americans up to age 70 need no more than 600 international units (IUs) of vitamin D per day to maintain health, and those 71 and older may need as much as 800 IUs, according to the Dietary Reference Intakes (DRIs) report from the Institute of Medicine.

The science on calcium’s role in bone health shows that 700 milligrams per day meets the needs of almost all children ages 1 through 3, and 1,000 milligrams daily is appropriate for almost all children ages 4 through 8. Adolescents ages 9 through 18 require no more than 1,300 milligrams per day.

For practically all adults ages 19 through 50 and for men until age 71, 1,000 milligrams covers daily calcium needs. Women starting at age 51 and both men and women age 71 and older need no more than 1,200 milligrams per day.

As for vitamin D, 600 IUs daily meets the needs of almost everyone in the United States and Canada, although people 71 and older may require as much as 800 IUs per day because of potential physical and behavioral changes related to aging.

Some adolescent girls may not get quite enough calcium, and there is a greater chance that elderly individuals may fall short of the necessary amounts of calcium and vitamin D. These individuals should increase their intake of foods containing these nutrients and possibly take a supplement.

Dilemma about D

Confusion about the amount of vitamin D necessary to ward off deficiency has arisen in recent years as tests that measure levels in patients’ blood have become widely used.

The measurements of sufficiency and deficiency—the cutpoints—that clinical laboratories use to report test results have not been based on rigorous scientific studies and are not standardized, meaning the same individual could be declared deficient or sufficient depending on which laboratory reads the test.

There may be an overestimation of the number of people with vitamin D deficiency because many labs appear to be using cutpoints that are higher than the evidence indicates are appropriate.

Although sunlight triggers the natural production of vitamin D in skin and contributes to people’s vitamin D levels, individuals’ sun exposure varies greatly and many people are told to minimize their exposure, so the committee assumed minimal sun exposure to establish the DRIs. The new intake levels for vitamin D cover the needs of individuals who get little sun.

Not too much

Greater amounts of food fortification and rising rates of supplement use have increased the chances that people consume high amounts of these nutrients. Getting too much calcium from dietary supplements has been associated with kidney stones, for example, while excessive vitamin D can damage the kidneys and heart.

“While it is too early to make definitive statements about the risks associated with routine high doses of vitamin D and calcium, people don’t need more than the amounts established in this report,” Ross says.

“Past cases such as hormone replacement therapy and high doses of beta carotene remind us that some therapies that seemed to show promise for treating or preventing health problems ultimately did not work out and even caused harm. This is why it is appropriate to approach emerging evidence about an intervention cautiously, but with an open mind.”

The new DRIs are based on more information and higher-quality study results than were available when the DRIs for these nutrients were first set in 1997. The old and new DRIs reflect different calculations and are not directly comparable.

The study was sponsored by the U.S. Department of Health and Human Services, U.S. Department of Agriculture, U.S. Department of Defense and Health Canada. Established in 1970 under the charter of the National Academy of Sciences, the Institute of Medicine provides independent, objective, evidence-based advice to policymakers, health professionals, the private sector, and the public.

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