MICHIGAN STATE (US) — A new study reveals substantial differences—by surgeon and institution—in the rates of follow-up surgeries for women who have undergone a partial mastectomy to treat breast cancer.
Those differences, which cannot be explained by a patient’s medical or treatment history, could affect both cancer recurrence and overall survival rates, according to the research, which appears in the Journal of the American Medical Association.
“A partial mastectomy is one of the most commonly performed cancer operations in the United States,” says Laurence McCahill, a surgeon with Michigan State University’s department of surgery and director of surgical oncology at The Lacks Cancer Center.
“Currently, there are no readily identifiable quality measures that allow for meaningful comparisons of breast cancer surgical outcomes among surgeons and hospitals. But the current U.S. health care environment calls for increasing accountability for physicians and hospitals as well as transparency of treatment results.”
About three-fourths of women battling breast cancer have a partial mastectomy, and nearly one in four of them at some point have another surgery (re-excision) to remove additional tissue.
A partial mastectomy intends to remove cancerous cells while maintaining maximum cosmetic appearance of the breast, but failure to remove all the cells during the initial operation requires additional surgery.
The additional operations can produce considerable psychological, physical, and economic stress for patients and delay use of recommended supplemental therapies, according to the study, which measured variation in re-excision rates across hospitals and surgeons from 2003 to 2008. The study included more than 2,200 women with invasive breast cancer from four locations across the country.
The results show rates of re-excision varied widely and were not tied to any discernible patient characteristics. The study highlights the value of multicenter observational studies to pinpoint the variability in health care across different regions and health systems, McCahill says.
“While the long-term effect of this variability is beyond the scope of our study, it is feasible that cancer recurrence and overall survival could be affected by differences in initial surgical care,” he says.
“The wide level of unexplained clinical variation itself represents a potential barrier to high-quality and cost-effective care of patients with breast cancer.”
The study was funded by a National Institutes of Health grant via the American Recovery and Reinvestment Act of 2009.
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