Children younger than 5 who live in economically disadvantaged areas have a greater risk of medication poisoning that results in being referred to a health care facility, a new study shows. The areas were rural, had high unemployment, and lower rates of high school graduation and household income.
“Understanding where there are geographic clusters of kids being exposed to medications that could hurt them gives us the opportunity to effectively intervene,” says Anthony Fabio, assistant professor of epidemiology at the University of Pittsburgh Public Health. “It also could help emergency clinicians to ask the right questions and perhaps zero in on a medication exposure when a child comes in with unexplained symptoms.”
For the study, published in the journal Clinical Toxicology, researchers analyzed 26,685 Pittsburgh Poison Center records of pharmaceutical drug exposures—typically defined as ingesting a medication—in children under 5 years old from 2006 through 2010. They mapped the exposures based on whether there was simply a call to the center and advice given for treatment at home, if necessary, or if the center staff felt the exposure warranted medical evaluation and referred the child to a nearby health care facility.
Mapping the exposures in this way revealed distinct “exposure” and “referral” locations, or geographic clusters, throughout western and central Pennsylvania. The exposure clusters generally encompass urban areas where people are perhaps more familiar with the Pittsburgh Poison Center’s hotline and, therefore, more likely to call.
The referral clusters are generally in more rural areas characterized by high unemployment. In these areas, the likelihood of a child under 5 being referred to a health care facility for a medication exposure is 3.2 times greater than elsewhere.
“More study is needed to determine exactly why this is, but we believe it could be related to fewer resources for child supervision—whether at home or at daycare centers in the community—increasing the likelihood of a small child finding and swallowing medication,” Fabio says.
“These results have become a real eye-opener for us,” says coauthor Anthony F. Pizon, chief of the UPMC Division of Medical Toxicology and associate professor of emergency medicine. “We now recognize the population of children most vulnerable to potentially harmful medication exposure. Our hope is that we can better tend to the needs of these children through Poison Center outreach efforts and more effectively prevent childhood poisonings.”
Researchers from the University of Pennsylvania and the University of California, San Diego, are coauthors of the study. The University of Pittsburgh Clinical and Translational Science Institute supported the work through a National Institutes of Health grant.
Source: University of Pittsburgh