Nurturing parents shield child’s brain from poverty

"This study gives us a feasible, tangible target with the suggestion that early interventions that focus on parenting may provide a tremendous payoff," says Joan L. Luby. (Credit: Jeff Meyer/Flickr)

Children living in poverty are more likely to have brain changes linked to depression and learning difficulties, but a new study shows the extent of those changes is influenced strongly by whether parents are nurturing.

Researchers used magnetic resonance imaging (MRI) and found that poor children with parents who were not very nurturing were likely to have less gray and white matter in the brain.

Gray matter is closely linked to intelligence. White matter often is linked to the brain’s ability to transmit signals between various cells and structures.

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The MRI scans also revealed that two key brain structures were smaller in children who were living in poverty: the amygdala, a key structure in emotional health, and the hippocampus, an area of the brain that is critical to learning and memory.

“We’ve known for many years from behavioral studies that exposure to poverty is one of the most powerful predictors of poor developmental outcomes for children,” says Joan L. Luby, a professor of psychiatry and director of the Early Emotional Development Program at Washington University in St. Louis.

“A growing number of neuroscience and brain-imaging studies recently have shown that poverty also has a negative effect on brain development.

“What’s new is that our research shows the effects of poverty on the developing brain, particularly in the hippocampus, are strongly influenced by parenting and life stresses that the children experience.”

Luby is in the midst of a long-term study of childhood depression. As part of the Preschool Depression Study, she has been following 305 healthy and depressed kids since they were in preschool. As the children have grown, they have received MRI scans that track brain development.

Size of the hippocampus

“We actually stumbled upon this finding,” she says. “Initially, we thought we would have to control for the effects of poverty, but as we attempted to control for it, we realized that poverty was really driving some of the outcomes of interest, and that caused us to change our focus to poverty, which was not the initial aim of this study.”

Researchers looked at scans from 145 children enrolled in the depression study. Some were depressed, others healthy, and others had been diagnosed with different psychiatric disorders such as ADHD (attention-deficit hyperactivity disorder).

As she studied these children, Luby says it became clear that poverty and stressful life events, which often go hand in hand, were affecting brain development.

The researchers measured poverty using what’s called an income-to-needs ratio, which takes a family’s size and annual income into account. The current federal poverty level is $23,550 for a family of four.

Although the investigators found that poverty had a powerful impact on gray matter, white matter, hippocampal, and amygdala volumes, they found that the main driver of changes among poor children in the volume of the hippocampus was not lack of money but the extent to which poor parents nurture their children.

The hippocampus is a key brain region of interest in studying the risk for impairments.

Luby’s team rated nurturing using observations made by the researchers—who were unaware of characteristics such as income level or whether a child had a psychiatric diagnosis—when the children came to the clinic for an appointment. On one of the clinic visits, the researchers rated parental nurturing using a test of the child’s impatience and of a parent’s patience with that child.

Patience and poverty

While waiting to see a health professional, a child was given a gift-wrapped package, and that child’s parent or caregiver was given paperwork to fill out. The child, meanwhile, was told that s/he could not open the package until the caregiver completed the paperwork, a task that researchers estimated would take about 10 minutes.

Parents living in poverty appeared more stressed and less able to be nurturing to their children during that exercise. In cases where poor parents were rated as good nurturers, the children were less likely to exhibit the same anatomical changes in the brain as poor children with less nurturing parents.

“Parents can be less emotionally responsive for a whole host of reasons,” Luby says. “They may work two jobs or regularly find themselves trying to scrounge together money for food. Perhaps they live in an unsafe environment.

“They may be facing many stresses, and some don’t have the capacity to invest in supportive parenting as much as parents who don’t have to live in the midst of those adverse circumstances.”

A ‘tremendous payoff’

The researchers also found that poorer children were more likely to experience stressful life events, which can influence brain development. Moving to a new house, changing schools, parents who fight regularly, and the death of a loved one are all considered a stressful life event.

The study, published in JAMA Pediatrics, could provide policymakers with at least a partial answer to the question of what it is about poverty that can be so detrimental to a child’s long-term developmental outcome, Luby says.

Because it appears that a nurturing parent or caregiver may prevent some of the changes in brain anatomy that this study identified, it is vital that society invest in public health prevention programs that target parental nurturing skills.

A key next step might be to determine if there are sensitive developmental periods when interventions with parents might have the most powerful impact.

“Children who experience positive caregiver support don’t necessarily experience the developmental, cognitive, and emotional problems that can affect children who don’t receive as much nurturing, and that is tremendously important,” Luby says.

“This study gives us a feasible, tangible target with the suggestion that early interventions that focus on parenting may provide a tremendous payoff.”

The National Institute of Mental Health funded the study.

Source: Washington University in St. Louis