Top Stories - Posted by Steven Adams-Missouri on Tuesday, December 27, 2011 10:25 - 4 Comments    
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Plasma brush: Pain-free fix for cavities

The plasma brush uses chemical reactions to disinfect and clean out cavities for fillings, in addition to forming a better bond for cavity fillings. (Credit: U. Missouri)

U. MISSOURI (US) — Researchers are one step closer to a painless way to replace fillings.





After favorable results in the lab, human clinical trials are under way on the “plasma brush.”

In less than 30 seconds, the plasma brush uses chemical reactions to disinfect and clean out cavities for fillings. In addition to the bacteria-killing properties, the “cool flame” from the plasma brush forms a better bond for cavity fillings.

The chemical reactions involved with the plasma brush actually change the surface of the tooth, which allows for a strong and robust bonding with the filling material.

“There have been no side effects reported during the lab trials, and we expect the human trials to help us improve the prototype,” say Qingsong Yu, associate professor of mechanical and aerospace engineering, and Meng Chen, chief scientist from Nanova, Inc., which holds a co-patent for the plasma brush with the University of Missouri.

“200 million tooth restorations cost Americans an estimated $50 billion a year, and it is estimated that replacement fillings comprise 75 percent of a dentist’s work. The plasma brush would help reduce those costs,” says Hao Li, associate professor of mechanical and aerospace engineering.

“In addition, a tooth can only support two or three restorations before it must be pulled. Our studies indicate that fillings are 60 percent stronger with the plasma brush, which would increase the filling lifespan. This would be a big benefit to the patient, as well as dentists and insurance companies.”

Human clinical trials are expected to begin in early 2012 at the University of Tennessee-Memphis. The researchers believe the human clinical trials will provide the data that allow Nanova to find investors and take the next steps in placing the product on the market.

If the studies go well and the FDA clears the use, the researchers’ timeline indicates the plasma brush could be available to dentists as early as the end of 2013.

The research and development team also includes Yong Wang from the School of Dentistry at University of Missouri-Kansas City and Liang Hong from the School of Dentistry at University of Tennessee-Memphis.

The project has been funded by the National Science Foundation and the National Institutes of Health. Li, along with Yu and Chen, have formed Nanova, Inc., with Chen leading the plasma brush device development through the NIH Small Business Innovation Research (SBIR) program.

More news from the University of Missouri: http://munews.missouri.edu/

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4 Comments

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wadudah nurul
Dec 27, 2011 16:24

wow…such a good invention.. love to have it soon

emc2
Dec 29, 2011 13:53

will dentists be willing to give up 75 percent of their business? (replacing old fillings.)

Trish
Dec 29, 2011 15:10

Sign me up! I have poor enamel and this would sure make my dentist trips better!!

andy
Mar 17, 2012 12:16

While it is very important to brush and floss every day to remove food particles and plaque, regular cleanings and checkups is the best way to help avoid cavities. Cavities occur as a result of the destruction of tooth structure, called tooth decay. great post.

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