Posts Tagged ‘mutations’

How ‘molecular machines’ evolved

U. CHICAGO / U. OREGON (US) — New research explains how a few genetic mutations may account for the evolution of complex “molecular machines.” Continue…

Wednesday, January 11, 2012 10:39 - 1 Comment

Health & Medicine - Feb 7, 2011 17:33 - 0 Comments

Cell metabolism linked to deadly tumors

DUKE (US) — The discovery that genetic mutations found in brain tumors can alter tumor metabolism could pave the way for targeted anti-cancer drug designs. (more…)

Health & Medicine - Jan 24, 2011 13:48 - 0 Comments

Mutation’s inside role in deafness

U. SHEFFIELD (UK) — A mutation of a specific microRNA appears to prevent development of the auditory sensory hair cells in the inner ear, leading to hearing loss and deafness. (more…)

Health & Medicine - Dec 29, 2010 11:14 - 2 Comments

Gene mutation linked to deadly lymphoma

U. ROCHESTER (US) — The discovery of a gene mutation that drives a form of lymphoma that’s often difficult to treat suggests a new route for therapy. (more…)

Health & Medicine - Dec 20, 2010 16:11 - 3 Comments

‘Whole new way in’ to brain tumors

BROWN U. (US) — A specific genetic mutation appears to be at the center of a metabolic meltdown associated with lethal brain tumors known as gliomas. (more…)

Health & Medicine - Jul 20, 2010 16:10 - 1 Comment

Computer predicts bacteria’s next move

DUKE (US)—Researchers are using computers to identify how one strain of dangerous bacteria might mutate in the same way a champion chess player tries to anticipate an opponent’s strategies. (more…)

Health & Medicine - Jun 4, 2010 9:49 - 3 Comments

Why H1N1 developed a resistance to Tamiflu

CALTECH (US)—Biologists have pinpointed molecular changes that helped allow the global spread of resistance to the antiviral medication Tamiflu (oseltamivir) among strains of the seasonal H1N1 flu virus. (more…)

Health & Medicine - Apr 13, 2010 10:52 - 3 Comments

Mapping human stem cells’ mutant DNA

U. SHEFFIELD (UK)—Scientists are closer to identifying and avoiding the adverse DNA changes that naturally occur when human embryonic stem cells are multiplied in the laboratory—changes that could hamper their future medical use. (more…)

Health & Medicine - Apr 1, 2010 12:34 - 0 Comments

Epilepsy model points out affected neurons

EMORY (US)—The creation of a mouse model of a genetic form of human epilepsy will allow scientists to dissect affected neurons and precisely define associated physiological changes. (more…)

Health & Medicine - Jan 15, 2010 17:16 - 4 Comments

Trigger: Stress kick starts tumor growth

YALE—New research shows stress sends signals that cause cells to develop into tumors. The findings reveal a novel way cancer takes hold in the body—and suggests new ways to attack the deadly disease. (more…)

Health & Medicine - Dec 22, 2009 17:28 - 6 Comments

Gene linked to both cleft lip, palate

U. IOWA (US)—An international research team has identified a gene that plays a major role in cleft lip and cleft palate. The findings could improve genetic counseling and potentially lead to improved treatment for the birth defect. (more…)

Health & Medicine - Dec 14, 2009 17:52 - 0 Comments

Cancer catalog advances targeted therapies

PRINCETON (US)—A systematic listing of the ways a particular cancerous cell has “gone wrong,” gives researchers a powerful tool that could eventually make possible new, more targeted therapies for patients. (more…)

Science & Technology - Dec 2, 2009 17:07 - 3 Comments

Team unravels mystery of ubiquitin chains

CALTECH (US)—Researchers have been able to view in detail, and for the first time, the previously unexplained process by which long chains of a protein called ubiquitin are added to proteins that control the cell cycle. The finding may one day lead to the development of targeted cancer therapies. (more…)

Science & Technology - Oct 27, 2009 11:54 - 0 Comments

Different color, same genetics

U. MICHIGAN (US)—Despite having different color pigmentation, members of the same species have the same genetic makeup, a new study finds. (more…)

Health & Medicine - Oct 26, 2009 15:52 - 6 Comments

Gene ‘cancer-proofs’ rodent’s cells

U. ROCHESTER (US)—Despite a 30-year lifespan that gives ample time for cells to grow cancerous, a small rodent species called a naked mole rat has never been found with tumors of any kind—and now biologists think they know why. (more…)

Science & Technology - Sep 10, 2009 12:37 - 0 Comments

Software speeds hunt for cancer triggers

Rachel Karchin, right, an assistant professor of biomedical engineering, and doctoral student Hannah Carter led a Johns Hopkins team that developed software to narrow the search for mutations linked to cancer. (Credit: Will Kirk/Johns Hopkins)

Science & Technology - Aug 20, 2009 4:00 - 0 Comments

Quantum dots catch cancer early

In this illustration, quantum dots are depicted as gold spheres that attract DNA strands linked to cancer risks. When the quantum dots are exposed to certain types of light, they transfer the energy to fluorescent molecules, shown as pink globes, that emit a glow. This enables researchers to detect and count the DNA strands linked to cancer. (Credit: Yi Zhang/ Johns Hopkins University)

Science & Technology - Mar 12, 2009 11:03 - 0 Comments

Researchers harness cold virus to fight HIV

Professors Eddy and Gail Ferstandig Arnold (Credit: Nick Romanenko)