Comments on: Glaucoma’s blindness starts in the brain http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/ Research news from leading universities Sun, 12 Feb 2012 00:52:25 +0000 hourly 1 http://wordpress.org/?v=3.0.4 By: Kathy http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-32492 Kathy Sun, 09 Jan 2011 06:30:50 +0000 http://futurity.org/?p=9933#comment-32492 I'm in my early 40's, and have recently been warned by my ophthalmologist that my intra-ocular pressure is raised, and I need to have it checked regularly. My mother has the early stages of glaucoma, and suffers from hearing loss and dementia. I've shared several of her other health problems including hypothyroidism, and migraines characterized by photo-sensitivity and aura. Recently I've developed annoying, frequent tinnitus that is worsened by stress. I share my concern with Irene, that the recent bouts with tinnitus seem to be related to increases in intra-ocular pressure, and it could be a warning sign of glaucoma. I believe it's worth a study. I’m in my early 40′s, and have recently been warned by my ophthalmologist that my intra-ocular pressure is raised, and I need to have it checked regularly. My mother has the early stages of glaucoma, and suffers from hearing loss and dementia. I’ve shared several of her other health problems including hypothyroidism, and migraines characterized by photo-sensitivity and aura. Recently I’ve developed annoying, frequent tinnitus that is worsened by stress. I share my concern with Irene, that the recent bouts with tinnitus seem to be related to increases in intra-ocular pressure, and it could be a warning sign of glaucoma. I believe it’s worth a study.

]]> By: june http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-29835 june Sun, 21 Nov 2010 11:49:00 +0000 http://futurity.org/?p=9933#comment-29835 Hi. My mom of 90 was diagnosed with glaucome and cataracts. The standard treatment of eye drops was prescribed and she attended the free clinic every 6 months. They decided to do a cataract op on the good eye to restore more sight. This failed dismally and she was blind from then on. She is now unable to walk and I cannot get her to the free clinic anymore. She gets two kinds of drops morning and evening plus a third one in the evening. The cost of the drops alone takes her whole pension for the month. As she is now totally blind, does she still need to use the drops or is there an alternative item that is not so expensive that she can use. Thank you June Hi. My mom of 90 was diagnosed with glaucome and cataracts. The standard treatment of eye drops was prescribed and she attended the free clinic every 6 months. They decided to do a cataract op on the good eye to restore more sight. This failed dismally and she was blind from then on. She is now unable to walk and I cannot get her to the free clinic anymore. She gets two kinds of drops morning and evening plus a third one in the evening. The cost of the drops alone takes her whole pension for the month. As she is now totally blind, does she still need to use the drops or is there an alternative item that is not so expensive that she can use. Thank you
June

]]> By: pathogenesis and treat glaucoma http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-20949 pathogenesis and treat glaucoma Mon, 18 Oct 2010 14:55:44 +0000 http://futurity.org/?p=9933#comment-20949 Dear colleague, my name is Evgeny Emelyanov. I would like test new hypothesis of pathogenesis and treat glaucoma, which can give new sight to a problem (save nerve optical, save vision). I don't found in all sources of information about study glaucoma the line of investigation like my. Now I try find university or center for experiment. Can I offer to you test jointly my hypothesis? If it will truth I really ready pass all rights to investigator. Yours faithfully , Evgeny Emelyanov 9109703511@mail.ru Dear colleague, my name is Evgeny Emelyanov.
I would like test new hypothesis of pathogenesis and treat glaucoma, which can give new
sight to a problem (save nerve optical, save vision). I don’t found in all sources of information
about study glaucoma the line of investigation like my. Now I try find university or center for experiment.
Can I offer to you test jointly my hypothesis?
If it will truth I really ready pass all rights to investigator.

Yours faithfully , Evgeny Emelyanov

9109703511@mail.ru

]]> By: Shuja Zaidi http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-20100 Shuja Zaidi Tue, 12 Oct 2010 15:13:41 +0000 http://futurity.org/?p=9933#comment-20100 There have been so certain hypotheses about Glaucoma. It has been said that Glaucoma is because of cupping. If that had been the case, why as of today there has not been any treatment for it. Dr. Syed Hasnain says its due to sinking and does make sense. Why not go ahead and open the door for further research on the hypothesis that Dr. Hasnain has come up with. If Dr. Hasnain is right then we can see many Glaucoma patients with a hope and start looking for cure of Glaucoma. More than 150 years passed by and as of today we are following the theory of cupping which has not taken us any where. I insist that most of the researchers should consider Dr. Hasnain's idea of Sinking and find a cure of Glaucoma. If he is right, then many people in this world will benefit from it. There have been so certain hypotheses about Glaucoma. It has been said that Glaucoma is because of cupping. If that had been the case, why as of today there has not been any treatment for it. Dr. Syed Hasnain says its due to sinking and does make sense. Why not go ahead and open the door for further research on the hypothesis that Dr. Hasnain has come up with. If Dr. Hasnain is right then we can see many Glaucoma patients with a hope and start looking for cure of Glaucoma. More than 150 years passed by and as of today we are following the theory of cupping which has not taken us any where. I insist that most of the researchers should consider Dr. Hasnain’s idea of Sinking and find a cure of Glaucoma. If he is right, then many people in this world will benefit from it.

]]> By: AroundHarlem http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-17995 AroundHarlem Mon, 09 Aug 2010 20:42:11 +0000 http://futurity.org/?p=9933#comment-17995 My brother has mild cerebral palsy (5%), he's 44 years old. When he was in his mid 30's he began getting eye drops because they noticed early stage glaucoma. We assumed it was hereditary because our great grandmother and her 2 sons had it. Any thoughts on glaucoma being hereditary? Are his chances increased because of the effects of cerebral palsy? Why does it occur more in African Americans? (Think I read that stat before.) My brother has mild cerebral palsy (5%), he’s 44 years old. When he was in his mid 30′s he began getting eye drops because they noticed early stage glaucoma. We assumed it was hereditary because our great grandmother and her 2 sons had it.

Any thoughts on glaucoma being hereditary?

Are his chances increased because of the effects of cerebral palsy?

Why does it occur more in African Americans? (Think I read that stat before.)

]]> By: Syed S. Hasnain http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-15110 Syed S. Hasnain Thu, 22 Jul 2010 04:43:36 +0000 http://futurity.org/?p=9933#comment-15110 I do not think glaucoma starts in the midbrain. Pathognomonic feature of chronic glaucoma are arcuate field defects in early stages of glaucoma. Arcuate axons lie above and below the macular fibers in the retina. Arcuate field defects are perhaps the only lead we have in finding the pathogenesis of glaucoma. Can the injury starting in the midbrain selectively destroy the arcuate fibers in the initial stages of glaucoma? I think it will be unlikely. I hypothesize that the primary pathology of glaucoma lies in the border tissue of Elschnig and not in Lamina cribrosa. Circular border tissue keeps the optic disc in place in the scleral canal as a 'O" ring seal. Border tissue atrophies due to chronic ischemia either due to high intraocular pressure or due to poor systemic cardio-pulmonary and circulatory problems. Due to atrophy of the border tissue the optic disc will start sinking in its entirety. Due to normally temporally tilted disc the temporal fibers consisting of superior and inferior arcuate and centrally located macular fibers will be stretched and severed against the scleral edge due to sinking disc earlier. Arcuate fibers being fewer in number compared to the macular will be depleted earlier giving rise to arcuate field defects. Sinking of the optic disc and severing of the axons are unique to glaucoma. Axotomy of the axons results in excavation of the disc which is characteristic of glaucoma unlike flat disc atrophy in which the axons are atrophied but not severed therefore no excavation of the disc in such cases. Sinking of the disc will become unstoppable akin to a sinking ship. Due to severance of the axons there will be retrograde degeneration of the ganglion cells of retina proximally and in the neurons in the LGN in midbrain and in the occipital cortex distally. i believe the primary pathology lies in border tissue around the optic disc and not in the midbrain. If the pathology at the level of midbrain can cause selective destruction of the arcuate fibers in the intial stages of glaucoma then it will be a interesting phenomenon. I do not think glaucoma starts in the midbrain. Pathognomonic feature of chronic glaucoma are arcuate field defects in early stages of glaucoma. Arcuate axons lie above and below the macular fibers in the retina. Arcuate field defects are perhaps the only lead we have in finding the pathogenesis of glaucoma. Can the injury starting in the midbrain selectively destroy the arcuate fibers in the initial stages of glaucoma? I think it will be unlikely.

I hypothesize that the primary pathology of glaucoma lies in the border tissue of Elschnig and not in Lamina cribrosa. Circular border tissue keeps the optic disc in place in the scleral canal as a ‘O” ring seal. Border tissue atrophies due to chronic ischemia either due to high intraocular pressure or due to poor systemic cardio-pulmonary and circulatory problems. Due to atrophy of the border tissue the optic disc will start sinking in its entirety. Due to normally temporally tilted disc the temporal fibers consisting of superior and inferior arcuate and centrally located macular fibers will be stretched and severed against the scleral edge due to sinking disc earlier. Arcuate fibers being fewer in number compared to the macular will be depleted earlier giving rise to arcuate field defects.

Sinking of the optic disc and severing of the axons are unique to glaucoma. Axotomy of the axons results in excavation of the disc which is characteristic of glaucoma unlike flat disc atrophy in which the axons are atrophied but not severed therefore no excavation of the disc in such cases. Sinking of the disc will become unstoppable akin to a sinking ship. Due to severance of the axons there will be retrograde degeneration of the ganglion cells of retina proximally and in the neurons in the LGN in midbrain and in the occipital cortex distally. i believe the primary pathology lies in border tissue around the optic disc and not in the midbrain. If the pathology at the level of midbrain can cause selective destruction of the arcuate fibers in the intial stages of glaucoma then it will be a interesting phenomenon.

]]> By: Irene http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-10596 Irene Tue, 23 Mar 2010 15:22:45 +0000 http://futurity.org/?p=9933#comment-10596 Hello! I am happy to hear the progress in the Glaucoma research. I have Tinnitus. The ringing in the ears, head noises. At times, I feel it is related with my Glaucoma. I feel like a vibration in the mid part of my head. It feels it comes from my Brain. When I first was diagnosed with Tinnitus.. I thought it was going to be the end of me. My ENT., doctor told me . . . as we get older we lose brain cells. I know when I got it. I was transcribing from dictation. Many times I raised the volume thinking I could hear better. I was having difficulty listening to it so I kept raising the volume higher and higher. At one point I felt I had a belt, tightening wrapped around my head. And a terrible headache developed. .After that I begun to hear the high pitch sounds, distrating ttoo. Ever since then I’ve had it. I am letting you know of my experience with Tinnitus. I think it is all related... When I go under the shower , the sounds deminishes for a litle while. If I get upset/and/or anxious / it exacerbates also. It is usually high but it can go low but not for a long time. It is depressing. I cannot get rid off of it... I hope that finally they can come up with a cure or at least making this noise get lower or go completely away! I've thought that it could be related with my Glaucoma. Fixed typographical errors. Hello!
I am happy to hear the progress in the Glaucoma research. I have Tinnitus. The ringing in the ears, head noises. At times, I feel it is related with my Glaucoma. I feel like a vibration in the mid part of my head. It feels it comes from my Brain. When I first was diagnosed with Tinnitus.. I thought it was going to be the end of me. My ENT., doctor told me . . . as we get older we lose brain cells. I know when I got it. I was transcribing from dictation. Many times I raised the volume thinking I could hear better. I was having difficulty listening to it so I kept raising the volume higher and higher. At one point I felt I had a belt, tightening wrapped around my head. And a terrible headache developed. .After that I begun to hear the high pitch sounds, distrating ttoo. Ever since then I’ve had it. I am letting you know of my experience with Tinnitus. I think it is all related… When I go under the shower , the sounds deminishes for a litle while. If I get upset/and/or anxious / it exacerbates also. It is usually high but it can go low but not for a long time. It is depressing. I cannot get rid off of it… I hope that finally they can come up with a cure or at least making this noise get lower or go completely away! I’ve thought that it could be related with my Glaucoma. Fixed typographical errors.

]]> By: Test http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-10595 Test Tue, 23 Mar 2010 13:29:07 +0000 http://futurity.org/?p=9933#comment-10595 Testy Testy

]]> By: Marina Bosi http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-10044 Marina Bosi Wed, 10 Mar 2010 21:36:26 +0000 http://futurity.org/?p=9933#comment-10044 Thank you so much dear professor! I have always thought that glaucoma is a neurodegenerative disease detectable monitoring the optic disk of our patients. A disregulation in the mid brain is responsible of a cascade of effects that determine also the optic nerve head glaucomatous atrophy. I agree with you. Please help me. Why the glaucomatous atrophy of the optic nerve is typical only of glaucoma? Why the progression of glaucoma is different in different patients? Is possible to detect distrophies and atrophies also in the primary occipital visual cortex in glaucomatous patients ? Why? Why is it not possible to see the typical glaucomatous atrophy in different diseases of the brain like in Alhzeimer and Parkinson?Is it because the first site of these diseases is not in the midbrain? I would like to know more. Congratulation! This new way of thinking Is like a Galileian revolution. Thank you so much dear professor! I have always thought that glaucoma is a neurodegenerative disease detectable monitoring the optic disk of our patients. A disregulation in the mid brain is responsible of a cascade of effects that determine also the optic nerve head glaucomatous atrophy. I agree with you.
Please help me. Why the glaucomatous atrophy of the optic nerve is typical only of glaucoma? Why the progression of glaucoma is different in different patients? Is possible to detect distrophies and atrophies also in the primary occipital visual cortex in glaucomatous patients ? Why? Why is it not possible to see the typical glaucomatous atrophy in different diseases of the brain like in Alhzeimer and Parkinson?Is it because the first site of these diseases is not in the midbrain? I would like to know more. Congratulation! This new way of thinking Is like a Galileian revolution.

]]> By: Irene http://www.futurity.org/health-medicine/glaucomas-blindness-startes-in-the-brain/comment-page-1/#comment-10033 Irene Wed, 10 Mar 2010 18:19:20 +0000 http://futurity.org/?p=9933#comment-10033 Hello! I am happy to hear the progress in the Glaucoma research. I have Tinnitus, rining in the ears, head noises..... I do feel at times is related with my Glaucoma. I feel like a little vibration in the middle of my head. Brain, at times. When I was first diagnosed with it. I thought it was going to be the end of me. the doctor told me as you get older you lose brain cells. I know when I got it. I was listening to dictation from a tape from psychologist dictating and I was having difficulty listening to it so I raised the volume loud many times, thinking I was going to hear better. At one point doing that I developed a tight belt around my head, and terrible headache.After thet the hight pitch distrating begaun to sound. Ever since I've had it. I am letting you knoe of my experience. When I go under the shower it deminishes. If I get upset/and/or anxious it exacerbates. It is usually high but it can go low but not for a long time. It is depressive, for I have no piece of mine and it is distracting too. I hope that finally they can come up with a cure or at least making this nice to go lower.... Hello!
I am happy to hear the progress in the Glaucoma research. I have Tinnitus, rining in the ears, head noises….. I do feel at times is related with my Glaucoma. I feel like a little vibration in the middle of my head. Brain, at times. When I was first diagnosed with it. I thought it was going to be the end of me. the doctor told me as you get older you lose brain cells. I know when I got it. I was listening to dictation from a tape from psychologist dictating and I was having difficulty listening to it so I raised the volume loud many times, thinking I was going to hear better. At one point doing that I developed a tight belt around my head, and terrible headache.After thet the hight pitch distrating begaun to sound. Ever since I’ve had it. I am letting you knoe of my experience. When I go under the shower it deminishes. If I get upset/and/or anxious it exacerbates. It is usually high but it can go low but not for a long time. It is depressive, for I have no piece of mine and it is distracting too. I hope that finally they can come up with a cure or at least making this nice to go lower….

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