Health & Medicine - Posted by Lois Baker-Buffalo on Monday, July 12, 2010 11:22 - 9 Comments    
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Agent Orange effects linger for Vietnam vets

U.S. Military planes cropdusting in Vietnam during Operation Ranch Hand which lasted from 1962 to 1971. (Credit: Wikimedia Commons)

U. BUFFALO (US)—Vietnam War-era veterans exposed to Agent Orange appear to have significantly more Graves’ disease, a thyroid disorder, than veterans with no exposure, a new study shows.

“The autoimmune disorder was three times more prevalent among veterans who encountered the dioxin-containing chemical,” says Ajay Varanasi, an endocrinology fellow at the University at Buffalo and first author on the study. “We also looked at other thyroid diagnoses, but we didn’t find any significant differences in thyroid cancer or nodules.”

Agent Orange is a defoliant that was used in Vietnam to destroy crops and reduce jungle foliage that could shelter enemy combatants. The herbicide contains dioxin, which has chemical properties similar to the thyroid hormones.

Graves’ disease is an autoimmune disease associated with overactivity of the thyroid gland. This gland releases the hormones that control body metabolism and are critical for regulating mood, weight, and mental and physical energy levels.

Varanasi and colleagues assessed the prevalence of major thyroid diagnoses in the Veterans Administration electronic medical record database for upstate New York veterans born between 1925 and 1953, the age group that would have been eligible for military service during the Vietnam era. They conducted the research at the Buffalo VA Medical Center.

They compared the frequency of diagnoses of thyroid cancer, nodules, hypothyroidism, and Graves’ disease in veterans who identified themselves as being exposed to Agent Orange (23,939) or not exposed to Agent Orange (200,109).

“Analyzing data on thyroid conditions, we found no difference in the prevalence of thyroid nodules or cancers between the exposed and non-exposed groups,” says Varanasi. “Graves’ disease, however, was three times more prevalent in the exposed group.

“Interestingly, hypothyroidism [lower than normal thyroid] was less common in the exposed group.”

Varanasi, who garnered first prize in the oral presentation category for this research at the American Association of Clinical Endocrinologists annual meeting held in Boston in April, says that in view of the known effects of dioxin on the immune system, further research should be conducted on the increased prevalence of Graves’ disease in Vietnam veterans. His research group is planning to continue this investigation either in vitro or in animal models.

More news from the University at Buffalo: www.buffalo.edu/news/

9 Comments

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chekawa
Jul 13, 2010 0:32

According to Senator Webb of VA any effects of Agent Orange in Vietnam Vets is related to old age. If that is so true then how come numerous studies presently and in the past are all wrong. Mr Webb has now become a doctor and a endocrinologists. He is pounding his chest and will now have hearing on the additional three disease’s the secretary of VA has added to the long and growing list. It looks like he has become a wolf in sheep’s clothing and is willing to sit back and watch a nation of vets linger in this cesspool of his creation that nothing is good for the men who took the oath to defend this country. But what does he care he is part of the problem . Go figure Mr Webb you call yourself a brother in arms?

Stephen Carey
Jul 18, 2010 16:29

chekawa, thank you for your comment. Senator Webb, is one of my senators, here in VA. I am about 10 minutes outside of DC – I think I always add that line so that people won’t think that I can’t think or that I won’t listen to any other ideas. I guess I still wished I lived in DC.

Anyway, I am very sorry about my Senator’s belief on this subject. There is so much information, real science information, that confirm that Agent Orange illnesses are still with us. I sometimes think that people would just like the great Viet Nam Vets of our country would just all disappear. Then, they don’t have to face the truth.

I was a kid during the war, but even then, I knew of some sort of medical issue with the defoliation this country used during that long war. I hold so much love in my heart for these men and women. My father was there, though, I don’t know what he did there, heck, we never knew what he did anywhere. Maybe those on the ground felt that they really needed this to win the war, plus, the military civilians and the upper echelon of the military kept telling those below them that what they were hearing was junk science. We now know it was not.

Finally, I am beyond tired, make it angry, when I hear that in the 1980s, it was then President Reagan how won the cold war for us. That totally dismisses all of those who died, were injured, served, and those dealing with the Agent Orange issues, didn’t contribute. Those 52,000 men and women did bring the close of the Cold War closer. The fact that the US would take such a tough stand on communism was absolutely in the minds of those at the Kremlin. And, what about the various CIA operations we will never know about, or, the Korean War – did they serve for any other reason than to help end the cold war?

I thank all of those who served and their families, for it can be so difficult on spouses and children. And, I pray, that those men and women coming home from our current battles find a better health care plan for them and that they will be followed for the rest of their lives.

Carolyn
Jul 23, 2010 2:04

June 26,2010 my husband took his life.He was type II diabetes and high blood pressure.
He had satted he had no energy and from stated sx. neuropathy.

He was a Vietnam Vet. can this type and cause produce severe depression/? Although he never said he was and when asked he would say there is nothing wrong.Or could this be related to PTSD.

Many people have many opinions as to why because he would be the last person in the world to do this!

Manu Ganji
Jul 23, 2010 6:46

Chemical warfare has never stopped at serving just the purpose. It always brought with it some side effects. Especially chemicals have a prolonged effect and it takes hell lot of time ( I doubt if it’s ever possible) to gain a complete understanding. It’s been so many years and still we find new effects of Agent Orange. sad.

Dean F Wurgler
Jul 30, 2010 18:41

I was in Veit Nam in 1962 and part of 1963 and i came home with very high blood pressure and dead skin on my feet and am still treating both,my blood pressure is so high the dr does not know why i have not had a heart attacke they can not it to come down they change the meds every time i go to the doctor.

Joe Martin
Aug 11, 2010 15:00

At age 55 I started having skin problems which was diagnosed as psoriasis by VA at the same time I came down with COPD and had prostrate surgery and still have remaining problems and am recieving treatments on all of them which all are incurable. I made an agent orange claim four years ago and have been denied twice to date and just put in my third appeal. I would like to hear some opinions.

Glenn
Aug 16, 2010 11:45

Maybe I am crazy, but I was in Vietnam, special forces, and there are only two of us left, out of our team and I guess I was never there. We were told to never talk about this and the government says they have no record of this

chekawa
Aug 16, 2010 13:21

Glenn: The Army knows where they send you. The record keeping when left to a over worked clerk does not always go down in ink or even entered at all. All those records that were made by units more than likely never reached back to the states.When the south fell to the north we all know those records were put over the side or just plain got burned. That’s why their was a big fire in the records center. No records no claim.

Examples of this: I was in a VA hospital state side while they had me AWOL in country (Nam) I also was listed as being in Laos but not AWOL. So go figure, don’t get distracted by the fact you are to not talk about it.. That means nothing today. Get someone to help you with your case. You had to be somewhere, Right? Go get what you earned. Don’t forget that they know a percentage of people will give up. SO DON’T YOU!

Joe: I wish I could help you. I’m no expert. After all I know more and more about less and less. Go to the DAV and ask for some help. You don’t have to be a member. They will help you with the claim. If your already doing this then maybe you need some legal help. Go here http://www.vawatchdog.org/ and ask Jim for some help about your claim. He can direct you down the right path. Better read his file on how to file a claim. Let us know how you make out.

Good luck Brothers

ALVIN E THOMAS
Aug 25, 2010 19:05

i am a 1964-1965 USN Vietnam Veteran. I did’nt know the whole Navy was cut out of VA benefits, along with the Air Force. i guess we were’nt there either! I would love to see those Veterans denied claims, march on Washington. Sit down on the capitol steps, until this is rectified. We were shelling Cambodia, when Pres. Johnson said, “we have no troops deployed to Cambodia”. According to the VA “prove that Agent Orange caused your problems”. KEEP YOUR POWDER DRY! Welcome home!

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